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Bluebird Bio Signs a Three-Year Research Collaboration with Novo Nordisk to Develop In-Vivo Genome Editing Therapies for Hemophilia A

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Bluebird Bio Signs a Three-Year Research Collaboration with Novo Nordisk to Develop In-Vivo Genome Editing Therapies for Hemophilia A

Shots:

  • Bluebird Bio to utilize its mRNA-based megaTAL technology providing a specific and efficient way to silence- edit or insert genetic components combining Novo Nordisk’s deep expertise in hemophilia research and therapeutics 
  • The focus of the collaboration is to identify gene therapy candidates for people with severe genetic diseases with initial interest of correcting FVIII-clotting factor deficiency providing lifetime free of factor replacement therapy
  • MegaTALs are single-chain fusion enzyme that combines to DNA cleaving processes of Homing Endonucleases (HEs) with the DNA binding region of transcription activator-like (TAL) effectors

Click here to­ read full press release/ article | Ref: Bluebird Bio | Image: Twitter


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